Riassunto analitico
The monitoring of carbon dioxide concentration in the human body plays a crucial
role in various clinical fields, particularly in conditions where respiratory function
is either impaired or artificially regulated. Among these, extracorporeal circula-
tion (ECC), employed in advanced life support treatments such as Extracorporeal
Membrane Oxygenation (ECMO) and cardiac surgery, requires continuous moni-
toring of blood gases to ensure adequate oxygenation and CO2 removal.
The regulation of CO2 directly affects the acid-base balance and pH homeosta-
sis, which are fundamental factors in maintaining physiological stability during
complex medical procedures.
This study focuses on the development of a monitoring system based on the
Sensirion SCD30 sensor, which utilizes Non-Dispersive Infrared (NDIR) technol-
ogy to detect CO2 dissolved in biological fluids. The variation in transmitted light
intensity allows for the determination of CO2 concentration through Lambert-
Beer’s Law.
A key component of the system is the hollow fiber oxygenator, a device that
enables efficient gas exchange between blood and the external environment, repli-
cating pulmonary function in the regulation of oxygen and CO levels.
The measurement system has been designed to simulate physiological condi-
tions and assess the sensor’s response in different configurations, including gas-
phase testing, liquid-phase testing (H2O), and blood-phase testing.
To enhance measurement accuracy in biological fluids, a custom-built NDIR
sensor has been developed, incorporating a 4.26 μm infrared diode and an infrared-
sensitive photodiode.
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