Riassunto analitico
The design of the current intraoperative OCTs and aberrometers prevent their combined use. The purpose of this study is to demonstrate the proof-of-concept of a combined anterior segment OCT and aberrometer that addresses this barrier by using a single light source. We built a combined SD-OCT system and Hartmann-Shack (HS) aberrometer that uses a single light beam. The system operates at a wavelength of 840nm. The beam is focused in the pupil plane to produce high-contrast OCT images of the anterior segment. The HS sensor collects part of the light returning from the retina to measure aberrations. The difference with standard HS aberrometers is that the beam reaching the retina is defocused. We create a stand-alone software to acquire wavefront measurements and a control electronics to synchronize our software together with the commercial OCT imaging one. We evaluated the aberrometer on a model eye that provides controlled amount of defocus and cylinder. A safety study has been made to validate the use of the system on human subjects. To assess the accuracy of the system, we compared the optometric parameters measured on 13 human subjects to those obtained using a clinical autorefractor. To evaluate intrasession repeatability, we acquired 5 consecutive refraction measurements on the right eye of a 43 y/o subject (SE = -2.50D). The same operator acquired 5 measurements on the same subject at 30-minute intervals to assess intersession repeatability. Each session consisted of 5 consecutive measurements. We demonstrated the proof-of-principle of combined anterior segment OCT and autorefraction using a single beam.
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